A very common issue faced by reptile owners is the loss of appetite in their leopard geckos. If your pet is not eating, it could be due to an impaction, which is similar to constipation in humans. You can check for this by feeling your gecko's abdomen. If it feels lumpy or you notice lumps, then it's possible that your gecko is impacted. To deal with this issue, take the following steps: Replace loose substrate in your gecko's enclosure with paper towels or specialized carpets . Avoid using bark, cat litter, or any other similar substance that could be harmful. Provide your gecko with a dish of calcium, as they may eat loose substrate as a substitute for calcium. Ensure that your gecko has access to plenty of fresh water and change it daily. Give your pet a warm soak for 10 minutes a few times a day, with water at a temperature similar to their normal blood temperature. Feed your gecko the right food. In the wild, they eat grubs, worms, spiders, and insects. In captivity, crickets are the most commonly available food. However, be careful not to feed them crickets that are too large. Never feed a cricket that is longer than the width of your gecko's head. You can also try wax worms or meal worms to entice your gecko's appetite. Consider breeding your own crickets to ensure they are the right size for your gecko. Give your gecko specialist vitamin supplements as recommended by your vet. If your leopard gecko does not start eating within a few days of following these suggestions, take them to a vet. Even if you cannot see or feel any abnormalities, it's still important to take them to a vet right away. Make sure to inform the vet of when your gecko stopped eating and any other details that may help with the diagnosis. read more info here